Loux fanned a career-high 11 batters and gave up six hits over six scoreless innings, taking a no-decision as the Class A Advanced Pelicans fell to the Kinston Indians, 1-0.
Loux fanned at least one batter an inning, ending his night by striking out the last two hitters to face him. He recorded 10 strikeouts on May 2 against Potomac, not earning a decision in that game either for his effort.
Loux entered Thursday's game having won three straight starts. He has not lost a game since May 13, when he gave up six runs in 4 2/3 innings against Lynchburg.
Loux was originally drafted sixth overall last June by the Diamondbacks. After discovering a torn muscle in the 6-foot-5 right-hander's shoulder, Arizona declined to sign him and Major League Baseball declared him a free agent. Loux drew the interest of several teams, ultimately signing with the Texas Rangers in November.
In his debut season, the 22-year-old Texas A&M product is 7-3 with a 3.18 ERA. Loux is third in the Carolina League with 92 strikeouts in 15 starts for the Pelicans, and his win total ties him for second on the circuit.
Joseph Ortiz (4-3) took the loss for Myrtle Beach, allowing a run on three hits and fanning three over the final three frames.
Chase Burnett drove in the only run of the game with an RBI single in the ninth. Adam Abraham opened the inning with a double, his second hit of the evening.