Carrillo will begin serving his suspension on Opening Day.
The 28-year-old out of the University of Miami split last season between Class A Advanced Lakeland and Double-A Erie, combining to go 3-6 with a 6.23 ERA in a dozen games. He appeared in three big league contests in 2009 for San Diego and was in Spring Training with the Astros in 2011.
Drafted by Kansas City out of high school in 2002, Carrillo has pitched in 111 Minor League games in eight seasons since 2005. He's 26-40 with a 5.25 ERA over 545 1/3 innings, primarily as a starter.
Carrillo was the Padres' first-round pick in 2005, going 18th overall, before current big leaguers like Jacoby Ellsbury (No. 23), Matt Garza (No. 25) and Colby Rasmus (No. 28). He was claimed off waivers by the Phillies in September 2010, reclaimed by the Padres six days later, then claimed again by Houston. He signed with the Tigers last June after being released by the Astros in April 2011.
Carrillo is the ninth player this year to be suspended by Major League Baseball for violating the Minor League drug program. He was mentioned in a January report by Miami New Times linking several players to a recently closed clinic in Miami that allegedly dispensed performance-enhancing substances.