Fort Myers Mighty Mussels Roster & Staff
Fort Myers Transactions
| Date | Transaction |
| 05/16/22 | RHP David Festa assigned to Cedar Rapids Kernels from Fort Myers Mighty Mussels. |
| 05/12/22 | CF Luis Baez assigned to Fort Myers Mighty Mussels from Twins Organization. |
| 05/12/22 | OF Kyler Fedko assigned to Cedar Rapids Kernels from Fort Myers Mighty Mussels. |
| 05/10/22 | Fort Myers Mighty Mussels placed RHP Logan Campbell on the 7-day injured list. |
| 05/10/22 | Fort Myers Mighty Mussels activated RHP Niklas Rimmel from the 7-day injured list. |
| 05/07/22 | Fort Myers Mighty Mussels released RHP Dylan Thomas. |
| 05/07/22 | Wichita Wind Surge sent RHP Blayne Enlow on a rehab assignment to Fort Myers Mighty Mussels. |
| 05/05/22 | Fort Myers Mighty Mussels placed SS Jesus Feliz on the 7-day injured list. Right elbow strain. |
| 05/05/22 | Fort Myers Mighty Mussels placed SS Jesus Feliz on the 7-day injured list. |
| 05/05/22 | SS Ernie Yake assigned to St. Paul Saints from Fort Myers Mighty Mussels. |
| 05/01/22 | Minnesota Twins sent RHP Sonny Gray on a rehab assignment to Fort Myers Mighty Mussels. |
| 05/01/22 | St. Paul Saints sent RHP Jordan Balazovic on a rehab assignment to Fort Myers Mighty Mussels. |