Knoxville Smokies Roster & Staff
CHC Transactions
| Date | Transaction |
| 12/15/25 | Chicago Cubs signed free agent RHP Esmerbin Guerrero to a minor league contract. |
| 12/15/25 | Chicago Cubs signed free agent LHP Fenuel James to a minor league contract. |
| 12/14/25 | Chicago Cubs signed free agent RHP Ruben Torres to a minor league contract. |
| 12/14/25 | Chicago Cubs signed free agent C Johan Gomez to a minor league contract. |
| 12/13/25 | RHP Saul Siri assigned to DSL Cubs Blue from DSL Cubs Red. |
| 12/13/25 | RHP Saul Siri assigned to DSL Cubs Blue from DSL Cubs Red. |
| 12/13/25 | RHP Saul Siri assigned to DSL Cubs Blue from DSL Cubs Red. |
| 12/13/25 | RHP Saul Siri assigned to DSL Cubs Blue from DSL Cubs Red. |
| 12/12/25 | DSL Cubs Blue released RHP Roni Dias. |
| 12/12/25 | RHP Collin Snider assigned to Iowa Cubs. |
| 12/12/25 | Chicago Cubs signed free agent RHP Collin Snider to a minor league contract. |
| 12/11/25 | Knoxville Smokies released RHP Wil Jensen. |
| 12/11/25 | South Bend Cubs released LHP Burl Carraway. |
| 12/10/25 | 3B Devin Ortiz assigned to Iowa Cubs. |
| 12/10/25 | RHP Zane Mills assigned to Iowa Cubs. |
| 12/10/25 | RHP Adam Stone assigned to Iowa Cubs. |
| 12/01/25 | RHP Sam Mettert assigned to ACL Cubs. |
| 12/01/25 | Chicago Cubs signed free agent RHP Sam Mettert to a minor league contract. |