Iowa Cubs Roster & Staff
CHC Transactions
| Date | Transaction |
| 09/30/22 | Chicago Cubs sent RF Michael Hermosillo outright to Iowa Cubs. |
| 09/27/22 | Iowa Cubs activated 2B Jared Young. |
| 09/27/22 | Chicago Cubs optioned 2B Jared Young to Iowa Cubs. |
| 09/24/22 | South Bend Cubs activated RHP Tyler Schlaffer from the 7-day injured list. |
| 09/23/22 | Tennessee Smokies activated C Jake Washer. |
| 09/22/22 | Myrtle Beach Pelicans released RHP Alberto Sojo. |
| 09/22/22 | LHP Riley Martin assigned to Tennessee Smokies from South Bend Cubs. |
| 09/22/22 | RHP Michael McAvene and assigned to Tennessee Smokies from South Bend Cubs. |
| 09/22/22 | Tennessee Smokies activated LHP Riley Martin. |
| 09/22/22 | RHP Michael McAvene and assigned to Tennessee Smokies from South Bend Cubs. |
| 09/22/22 | LHP Riley Martin assigned to Tennessee Smokies from South Bend Cubs. |
| 09/21/22 | Chicago Cubs optioned RHP Jeremiah Estrada to Iowa Cubs. |
| 09/20/22 | Chicago Cubs sent LHP Steven Brault on a rehab assignment to Iowa Cubs. |
| 09/20/22 | Iowa Cubs activated RHP Kyle Johnson. |
| 09/20/22 | Iowa Cubs activated RHP Peyton Remy. |
| 09/20/22 | RHP Peyton Remy assigned to Iowa Cubs from Tennessee Smokies. |
| 09/20/22 | RHP Kyle Johnson assigned to Iowa Cubs from Tennessee Smokies. |
| 09/20/22 | Tennessee Smokies transferred C Jake Washer to the Development List. |
| 09/20/22 | RHP Peyton Remy assigned to Iowa Cubs from Tennessee Smokies. |
| 09/20/22 | RHP Kyle Johnson assigned to Iowa Cubs from Tennessee Smokies. |
| 09/19/22 | Chicago Cubs sent LHP Sean Newcomb outright to Iowa Cubs. |
| 09/18/22 | RHP Richard Gallardo assigned to Tennessee Smokies from South Bend Cubs. |
| 09/18/22 | RHP Richard Gallardo assigned to Tennessee Smokies from South Bend Cubs. |
| 09/17/22 | Chicago Cubs selected the contract of 3B Esteban Quiroz from Iowa Cubs. |
| 09/16/22 | Chicago Cubs sent RHP Keegan Thompson on a rehab assignment to Iowa Cubs. |
| 09/15/22 | 2B Christian Donahue assigned to Iowa Cubs from Tennessee Smokies. |
| 09/15/22 | RHP Blake Whitney assigned to Tennessee Smokies from Iowa Cubs. |
| 09/15/22 | Tennessee Smokies activated RHP Blake Whitney. |
| 09/15/22 | Tennessee Smokies activated RHP Blake Whitney. |
| 09/15/22 | RHP Blake Whitney assigned to Tennessee Smokies from Iowa Cubs. |
| 09/15/22 | 2B Christian Donahue assigned to Iowa Cubs from Tennessee Smokies. |
| 09/15/22 | Chicago Cubs signed free agent C David Avitia to a minor league contract. |
| 09/14/22 | Chicago Cubs selected the contract of 2B Jared Young from Iowa Cubs. |
| 09/14/22 | Tennessee Smokies placed LHP Jordan Wicks on the 7-day injured list. |
| 09/13/22 | SS Luis Vazquez assigned to Tennessee Smokies from Iowa Cubs. |
| 09/13/22 | SS Scott McKeon assigned to Iowa Cubs from Tennessee Smokies. |
| 09/13/22 | Myrtle Beach Pelicans activated CF Jacob Wetzel from the 7-day injured list. |
| 09/13/22 | Tennessee Smokies activated SS Luis Vazquez. |
| 09/13/22 | Tennessee Smokies activated OF D.J. Artis from the 60-day injured list. |
| 09/13/22 | SS Luis Vazquez assigned to Tennessee Smokies from Iowa Cubs. |
| 09/13/22 | SS Scott McKeon assigned to Iowa Cubs from Tennessee Smokies. |
| 09/12/22 | Myrtle Beach Pelicans activated RHP Tyler Santana from the 7-day injured list. |
| 09/12/22 | Tennessee Smokies placed C Miguel Amaya on the 7-day injured list. |
| 09/12/22 | Tennessee Smokies placed 2B Andy Weber on the 7-day injured list. |
| 09/12/22 | Tennessee Smokies placed 2B Andy Weber on the 7-day injured list. |
| 09/12/22 | Tennessee Smokies placed C Miguel Amaya on the 7-day injured list. |
| 09/11/22 | Tennessee Smokies activated LHP DJ Herz. |
| 09/11/22 | Tennessee Smokies activated LHP DJ Herz. |
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