San Antonio Missions Roster & Staff
San Antonio Transactions
| Date | Transaction |
| 04/30/25 | San Antonio Missions placed OF Tyler Robertson on the 7-day injured list. |
| 04/30/25 | SS Chase Valentine assigned to San Antonio Missions from ACL Padres. |
| 04/29/25 | San Antonio Missions sent RHP Sam Whiting on a rehab assignment to Lake Elsinore Storm. |
| 04/29/25 | San Antonio Missions activated LHP Fernando Sanchez. |
| 04/29/25 | LHP Fernando Sanchez assigned to San Antonio Missions from Fort Wayne TinCaps. |
| 04/27/25 | San Antonio Missions activated C Jack Mathey. |
| 04/27/25 | San Diego Padres selected the contract of RHP David Morgan from San Antonio Missions. |
| 04/26/25 | San Antonio Missions placed C Ethan Salas on the 7-day injured list. |
| 04/26/25 | San Antonio Missions placed C Ethan Salas on the 7-day injured list. |
| 04/23/25 | C Jack Mathey assigned to San Antonio Missions from ACL Padres. |
| 04/08/25 | LHP Jake Higginbotham assigned to San Antonio Missions from El Paso Chihuahuas. |
| 04/04/25 | San Antonio Missions placed C Andy Thomas on the restricted list. |
| 04/04/25 | San Antonio Missions placed RHP Cole Paplham on the 7-day injured list. |
| 04/04/25 | San Antonio Missions placed LHP Jackson Smeltz on the 7-day injured list. |
| 04/04/25 | San Antonio Missions placed RHP Sam Whiting on the 7-day injured list. |
| 04/01/25 | LHP Austin Krob assigned to El Paso Chihuahuas from San Antonio Missions. |