San Antonio Missions Roster & Staff
SD Transactions
| Date | Transaction |
| 06/03/25 | San Antonio Missions sent RHP Cole Paplham on a rehab assignment to Fort Wayne TinCaps. |
| 06/03/25 | San Diego Padres signed free agent C Antonio Alcala to a minor league contract. |
| 06/01/25 | DSL Padres Brown activated RHP Randoll Cruz. |
| 06/01/25 | RHP Albert Perez assigned to DSL Padres Brown. |
| 06/01/25 | DSL Padres Brown activated RHP Kelvin Marte. |
| 06/01/25 | DSL Padres Brown activated C Mathews Sosa. |
| 06/01/25 | OF Frederick Saguita assigned to DSL Padres Brown. |
| 06/01/25 | SS Eliander Primera assigned to DSL Padres Brown. |
| 06/01/25 | RHP Jeuris Guzman assigned to DSL Padres Brown. |
| 06/01/25 | DSL Padres Brown activated SS Eliander Primera. |
| 06/01/25 | DSL Padres Brown activated OF Frederick Saguita. |
| 06/01/25 | DSL Padres Brown activated IF Ariel Dilone. |
| 06/01/25 | RHP Dalvi Nunez assigned to DSL Padres Brown. |
| 06/01/25 | C Mathews Sosa assigned to DSL Padres Brown. |
| 06/01/25 | OF Cristian Benavides assigned to DSL Padres Brown from DSL Padres Gold. |
| 06/01/25 | RHP Wilkins Matos assigned to DSL Padres Brown from DSL Padres Gold. |
| 06/01/25 | RHP Randoll Cruz assigned to DSL Padres Brown from DSL Padres Gold. |
| 06/01/25 | RHP Daniel Burciaga assigned to DSL Padres Brown from DSL Padres Gold. |
| 06/01/25 | RHP Yoesmerli Beltre assigned to DSL Padres Brown from DSL Padres Gold. |
| 06/01/25 | LHP Gensy Aquino assigned to DSL Padres Brown from DSL Padres Gold. |
| 06/01/25 | 3B Alexander Garcia assigned to DSL Padres Gold from DSL Padres Brown. |
| 06/01/25 | LHP Alexis Parra assigned to DSL Padres Gold from DSL Padres Brown. |
| 06/01/25 | LHP Jeronimo Palmeros assigned to DSL Padres Gold from DSL Padres Brown. |
| 06/01/25 | RHP Miguel Angel Ledesma assigned to DSL Padres Gold from DSL Padres Brown. |
| 06/01/25 | RHP Jose Ortega assigned to DSL Padres Gold from DSL Padres Brown. |
| 06/01/25 | C Isaac Ponce assigned to DSL Padres Gold from DSL Padres Brown. |
| 06/01/25 | IF Fabian Alcantara assigned to DSL Padres Gold from DSL Padres Brown. |
| 06/01/25 | C Andres Garza assigned to DSL Padres Brown from DSL Padres Gold. |
| 06/01/25 | RHP Rordy Mejia assigned to DSL Padres Gold from DSL Padres Brown. |
| 06/01/25 | SS Deivid Coronil assigned to DSL Padres Gold from DSL Padres Brown. |
| 06/01/25 | IF Ariel Dilone assigned to DSL Padres Brown from DSL Padres Gold. |
| 06/01/25 | RHP Kelvin Marte assigned to DSL Padres Brown from DSL Padres Gold. |
| 06/01/25 | LHP Marco Eluscat assigned to DSL Padres Brown from DSL Padres Gold. |
| 06/01/25 | SS Kevin Tamburini assigned to DSL Padres Gold from DSL Padres Brown. |
| 06/01/25 | LHP Joseph Herrera assigned to DSL Padres Gold from DSL Padres Brown. |
| 06/01/25 | C Jhojan Downer assigned to DSL Padres Gold from DSL Padres Brown. |
| 06/01/25 | 2B Eduarlin Tejeda assigned to DSL Padres Gold from DSL Padres Brown. |
| 06/01/25 | OF Eddson Martinez assigned to DSL Padres Gold from DSL Padres Brown. |
| 06/01/25 | OF Sebastian Pena assigned to DSL Padres Gold from DSL Padres Brown. |
| 06/01/25 | RHP Edinson Hernandez assigned to DSL Padres Gold from DSL Padres Brown. |
| 06/01/25 | RHP Raymel Belliard assigned to DSL Padres Gold from DSL Padres Brown. |
| 06/01/25 | LHP Edwyn Hernandez assigned to DSL Padres Gold from DSL Padres Brown. |
| 06/01/25 | SS Abraham Bastidas assigned to DSL Padres Brown from DSL Padres Gold. |
| 06/01/25 | 2B Darian Castillo assigned to DSL Padres Brown from DSL Padres Gold. |
| 06/01/25 | SS Kaden Hernandez assigned to DSL Padres Brown from DSL Padres Gold. |
| 06/01/25 | DSL Padres Gold activated OF Eddson Martinez. |
| 06/01/25 | DSL Padres Gold activated LHP Edwyn Hernandez. |
| 06/01/25 | DSL Padres Gold activated SS Deivid Coronil. |
| 06/01/25 | C Alberto Enriche assigned to DSL Padres Gold. |
| 06/01/25 | RHP Florangel Vasquez assigned to DSL Padres Gold. |