Portland Sea Dogs Roster & Staff
Portland Transactions
| Date | Transaction |
| 05/17/22 | LHP Kyle Hart assigned to Portland Sea Dogs from Worcester Red Sox. |
| 05/17/22 | RHP Andrew Politi assigned to Worcester Red Sox from Portland Sea Dogs. |
| 05/17/22 | RHP Brayan Bello assigned to Worcester Red Sox from Portland Sea Dogs. |
| 05/17/22 | RHP Darin Gillies assigned to Portland Sea Dogs from Worcester Red Sox. |
| 05/13/22 | Portland Sea Dogs activated CF Wil Dalton from the 7-day injured list. |
| 05/13/22 | Portland Sea Dogs placed SS Cameron Cannon on the 7-day injured list retroactive to May 12, 2022. |
| 05/03/22 | OF Tyler Esplin assigned to Greenville Drive from Portland Sea Dogs. |
| 05/03/22 | SS Nick Sogard assigned to Portland Sea Dogs from Worcester Red Sox. |
| 05/01/22 | Portland Sea Dogs activated 1B Tyreque Reed. |
| 05/01/22 | Portland Sea Dogs activated RHP Jake Thompson. |