South Bend Cubs Roster & Staff
CHC Transactions
| Date | Transaction |
| 04/18/25 | South Bend Cubs placed RHP Jose Romero on the full-season injured list. |
| 04/16/25 | Iowa Cubs activated C Caleb Knight. |
| 04/16/25 | RHP Caleb Kilian assigned to Iowa Cubs. |
| 04/16/25 | Iowa Cubs placed 2B Dixon Machado on the 7-day injured list. |
| 04/16/25 | Chicago Cubs signed free agent RHP Caleb Kilian to a minor league contract. |
| 04/15/25 | Chicago Cubs sent RHP Javier Assad on a rehab assignment to Iowa Cubs. |
| 04/15/25 | Chicago Cubs sent RHP Tyson Miller on a rehab assignment to Iowa Cubs. |
| 04/15/25 | Chicago Cubs recalled LHP Luke Little from Iowa Cubs. |
| 04/15/25 | Chicago Cubs recalled RHP Daniel Palencia from Iowa Cubs. |
| 04/15/25 | Chicago Cubs optioned RHP Nate Pearson to Iowa Cubs. |
| 04/15/25 | Chicago Cubs optioned 2B Matt Shaw to Iowa Cubs. |
| 04/15/25 | SS Corey Joyce assigned to Knoxville Smokies. |
| 04/15/25 | South Bend Cubs transferred C David Avitia to the Development List. |
| 04/15/25 | South Bend Cubs activated SS Jefferson Rojas from the 7-day injured list. |
| 04/15/25 | Chicago Cubs signed free agent SS Corey Joyce to a minor league contract. |
| 04/13/25 | LHP Chase Watkins assigned to South Bend Cubs from Iowa Cubs. |
| 04/13/25 | LHP Chase Watkins assigned to South Bend Cubs from Iowa Cubs. |
| 04/12/25 | DSL Cubs Blue released RHP Jorge Alvarez. |
| 04/12/25 | RHP Nolan Clenney assigned to South Bend Cubs from Iowa Cubs. |
| 04/12/25 | LHP Chase Watkins assigned to Iowa Cubs from South Bend Cubs. |
| 04/12/25 | RHP Ryan Gallagher assigned to South Bend Cubs. |
| 04/12/25 | RHP Nolan Clenney assigned to South Bend Cubs from Iowa Cubs. |
| 04/12/25 | LHP Chase Watkins assigned to Iowa Cubs from South Bend Cubs. |
| 04/11/25 | LHP Christian Gordon assigned to Myrtle Beach Pelicans from ACL Cubs. |
| 04/11/25 | DSL Cubs Blue activated RHP Chaily Ramirez from the restricted list. |
| 04/11/25 | Myrtle Beach Pelicans placed RHP Jeral Vizcaino on the reserve list. |
| 04/11/25 | LHP Christian Gordon assigned to Myrtle Beach Pelicans from ACL Cubs. |
| 04/10/25 | LHP Tom Cosgrove assigned to Iowa Cubs. |
| 04/10/25 | RHP Nolan Clenney assigned to Iowa Cubs from South Bend Cubs. |
| 04/10/25 | RHP Nolan Clenney assigned to Iowa Cubs from South Bend Cubs. |
| 04/09/25 | LHP Evan Taylor assigned to ACL Cubs. |
| 04/09/25 | Chicago Cubs sent SS Vidal Bruján on a rehab assignment to Iowa Cubs. |
| 04/09/25 | Chicago Cubs sent SS Vidal Bruján on a rehab assignment to Iowa Cubs. |
| 04/09/25 | Chicago Cubs recalled RHP Ethan Roberts from Iowa Cubs. |
| 04/09/25 | Knoxville Smokies placed C Haydn McGeary on the 7-day injured list. |
| 04/09/25 | OF Brett Bateman assigned to Knoxville Smokies. |
| 04/09/25 | Knoxville Smokies placed C Haydn McGeary on the 7-day injured list. |
| 04/08/25 | Chicago Cubs signed free agent LHP Evan Taylor to a minor league contract. |
| 04/07/25 | DSL Cubs Blue activated LHP Frankelly Desis from the restricted list. |
| 04/05/25 | Iowa Cubs activated RHP Connor Noland. |
| 04/05/25 | Iowa Cubs placed RHP Caleb Kilian on the 7-day injured list. |
| 04/04/25 | LHP Ethan Flanagan assigned to Myrtle Beach Pelicans from ACL Cubs. |
| 04/04/25 | Knoxville Smokies transferred RHP Joe Nahas to the Development List. |
| 04/04/25 | Knoxville Smokies transferred RHP Carlo Reyes to the Development List. |
| 04/04/25 | Knoxville Smokies transferred RHP Antonio Santos to the Development List. |
| 04/04/25 | Myrtle Beach Pelicans placed RHP Landon Ginn on the 7-day injured list. |
| 04/04/25 | Myrtle Beach Pelicans placed CF Ismael Mena on the 7-day injured list. |
| 04/04/25 | LHP Ethan Flanagan assigned to Myrtle Beach Pelicans from ACL Cubs. |
| 04/04/25 | South Bend Cubs placed RHP Grayson Moore on the 7-day injured list. |
| 04/04/25 | South Bend Cubs placed SS Christian Olivo on the 7-day injured list. |