Greene, currently an All-Star outfielder for the Detroit Tigers, was the 5th overall selection in the 2019 Major League Baseball Draft out of Paul J. Hagerty High School in Oviedo, Florida. Greene would go on to make his debut with the Whitecaps later that summer, becoming the first millennial to don a Whitecaps jersey. Greene made his presence felt right from the get-go in West Michigan, making two ESPN SportsCenter Top 10 plays in his debut: a diving catch in centerfield and an inside-the-park home run. Over 24 games in 2019, Greene had 22 hits and knocked in 13 runs, while recording a perfect fielding percentage defensively. In 2021, Greene represented the Tigers at the All-Star Futures Game.
After quickly climbing the minor league ladder, Greene made his Major League Baseball debut for the Tigers in 2022. Then, in 2024 he was selected to the MLB All-Star Game and helped the Tigers reach the post-season for the first time in a decade.