Indianapolis Indians Roster & Staff
PIT Transactions
| Date | Transaction |
| 04/19/22 | Pittsburgh Pirates sent LHP Sam Howard on a rehab assignment to Indianapolis Indians. |
| 04/19/22 | Pittsburgh Pirates sent LF Anthony Alford on a rehab assignment to Indianapolis Indians. |
| 04/18/22 | Altoona Curve transferred LHP Zach Matson to the Development List. |
| 04/18/22 | Pittsburgh Pirates optioned RHP Luis Oviedo to Altoona Curve. |
| 04/17/22 | Pittsburgh Pirates sent RHP Luis Oviedo on a rehab assignment to Altoona Curve. |
| 04/16/22 | Pittsburgh Pirates sent LF Anthony Alford on a rehab assignment to Bradenton Marauders. |
| 04/15/22 | Altoona Curve activated C Dylan Shockley. |
| 04/15/22 | Altoona Curve activated OF Daniel Amaral. |
| 04/15/22 | Bradenton Marauders activated OF Randy Romero. |
| 04/15/22 | Pittsburgh Pirates sent LHP Sam Howard on a rehab assignment to Bradenton Marauders. |
| 04/12/22 | OF Randy Romero roster status changed by Bradenton Marauders. |
| 04/12/22 | Pittsburgh Pirates sent RHP Max Kranick on a rehab assignment to Bradenton Marauders. |
| 04/12/22 | Indianapolis Indians activated RHP Austin Brice. |
| 04/10/22 | Pittsburgh Pirates sent RHP Luis Oviedo on a rehab assignment to Bradenton Marauders. |
| 04/09/22 | Pittsburgh Pirates recalled RHP Roansy Contreras, and from Indianapolis Indians. |
| 04/08/22 | Altoona Curve transferred C Dylan Shockley to the Development List. |
| 04/08/22 | Altoona Curve transferred OF Daniel Amaral to the Development List. |
| 04/08/22 | Altoona Curve placed RHP Jeffrey Passantino on the 60-day injured list. |
| 04/08/22 | Altoona Curve placed RHP Quinn Priester on the 7-day injured list. Oblique. |
| 04/08/22 | OF Fabricio Macias assigned to Altoona Curve. |
| 04/08/22 | Bradenton Marauders placed RHP Jose Maldonado on the 60-day injured list. |
| 04/08/22 | RHP Drew Irvine assigned to Bradenton Marauders. |
| 04/08/22 | Bradenton Marauders placed RHP Drake Fellows on the 60-day injured list. |
| 04/08/22 | Bradenton Marauders placed RHP Enmanuel De Los Santos on the 7-day injured list. |
| 04/08/22 | RHP Owen Sharts assigned to Bradenton Marauders from FCL Pirates Gold. |
| 04/08/22 | RHP Mario Garcia assigned to Bradenton Marauders from FCL Pirates Gold. |
| 04/08/22 | RHP Brennan Malone assigned to Bradenton Marauders from FCL Pirates Gold. |
| 04/08/22 | RHP Brandan Bidois assigned to Bradenton Marauders from FCL Pirates Gold. |
| 04/08/22 | C Jhan Polanco assigned to Bradenton Marauders from FCL Pirates Black. |
| 04/08/22 | RHP Jack Hartman assigned to Bradenton Marauders from Greensboro Grasshoppers. |
| 04/08/22 | C Jhan Polanco assigned to Bradenton Marauders from FCL Pirates Black. |
| 04/08/22 | RHP Jack Hartman assigned to Bradenton Marauders from Greensboro Grasshoppers. |
| 04/08/22 | C Jhan Polanco assigned to Bradenton Marauders from FCL Pirates Black. |
| 04/08/22 | C Jhan Polanco assigned to Bradenton Marauders from FCL Pirates Black. |
| 04/08/22 | RHP Jack Hartman assigned to Bradenton Marauders from Greensboro Grasshoppers. |
| 04/08/22 | Greensboro Grasshoppers placed RHP Braxton Ashcraft on the 60-day injured list. |
| 04/08/22 | RHP Jack Hartman assigned to Bradenton Marauders from Greensboro Grasshoppers. |
| 04/08/22 | Pittsburgh Pirates signed free agent C Lennyn Nunez to a minor league contract. |
| 04/07/22 | SS Tucupita Marcano assigned to Altoona Curve. |
| 04/07/22 | SS Liover Peguero assigned to Altoona Curve. |
| 04/07/22 | Altoona Curve activated SS Andrés Alvarez. |
| 04/07/22 | Altoona Curve placed RHP Aaron Shortridge on the 60-day injured list. |
| 04/07/22 | Altoona Curve activated SS Andres Alvarez. |
| 04/07/22 | Altoona Curve placed 3B Jared Triolo on the 7-day injured list. Left knee. |