Below is a list of all the former Shorebirds that have made it to the Major Leagues, not including rehab stints. The star-studded list includes: Orlando Cabrera, Javier Vazquez, Brian Roberts, Nick Markakis, Manny Machado and many others. The players are ordered by year in which they played for the Shorebirds starting with the inaugural 1996 club.
| Name | MLB Debut | With Shorebirds | Debut Team | |
|---|---|---|---|---|
| 1 | Orlando Cabrera | 9/3/97 | 1996 | Montreal |
| 2 | Javier Vazquez | 4/3/98 | 1996 | Montreal |
| 3 | Jeremy Powell | 7/23/98 | 1996 | Montreal |
| 4 | Fernando Seguignol | 9/5/98 | 1996 | Montreal |
| 5 | Michael Barrett | 9/19/98 | 1996 | Montreal |
| 6 | J.D. Smart | 4/6/99 | 1996 | Montreal |
| 7 | Jose Macias | 5/12/99 | 1996 | Detroit |
| 8 | Jose Fernandez | 7/3/99 | 1996 | Montreal |
| 9 | Brian Schneider | 5/26/00 | 1996 | Montreal |
| 10 | Troy Mattes | 6/19/01 | 1996 | Montreal |
| 11 | Radhames Dykhoff | 6/7/98 | 1997 | Baltimore |
| 12 | Calvin Pickering | 7/12/98 | 1997 | Baltimore |
| 13 | Ryan Minor | 9/13/98 | 1997 | Baltimore |
| 14 | Gabe Molina | 5/1/99 | 1997 | Baltimore |
| 15 | Brian Falkenborg | 10/1/99 | 1997 | Baltimore |
| 16 | Ivanon Coffie | 7/15/00 | 1997 | Baltimore |
| 17 | John Parris | 7/24/00 | 1997 | Baltimore |
| 18 | Ryan Kohlmeier | 7/29/00 | 1997 | Baltimore |
| 19 | Carlos Casimiro | 7/31/00 | 1997 | Baltimore |
| 20 | Chad Paronto | 4/18/01 | 1997 | Baltimore |
| 21 | Josh Towers | 5/2/01 | 1997 | Baltimore |
| 22 | Luis Matos | 6/19/00 | 1997, 1998 | Baltimore |
| 23 | Rick Bauer | 9/2/01 | 1997, 1998 | Baltimore |
| 24 | Eddy Garabito | 5/27/05 | 1997, 1998 | Colorado |
| 25 | Matt Riley | 9/9/99 | 1998 | Baltimore |
| 26 | Jay Spurgeon | 8/15/00 | 1998 | Baltimore |
| 27 | Jayson Werth | 9/1/02 | 1998 | Toronto |
| 28 | Darnell McDonald | 5/30/04 | 1998 | Baltimore |
| 29 | John Stephens | 7/30/02 | 1998, 1999 | Baltimore |
| 30 | Brian Roberts | 6/14/01 | 1999 | Baltimore |
| 31 | Larry Bigbie | 6/23/01 | 1999 | Baltimore |
| 32 | Tim Raines, Jr. | 9/1/01 | 1999 | Baltimore |
| 33 | Steve Bechler | 7/6/02 | 1999 | Baltimore |
| 34 | Aaron Rakers | 7/8/04 | 1999 | Baltimore |
| 35 | Willie Harris | 7/2/01 | 1999, 2000 | Baltimore |
| 36 | Keith Reed | 5/11/05 | 1999, 2000 | Baltimore |
| 37 | Napoleon Calzado | 5/29/05 | 1999, 2000 | Baltimore |
| 38 | Erik Bedard | 4/17/02 | 2000 | Baltimore |
| 39 | Eddie Rogers | 7/5/02 | 2000 | Baltimore |
| 40 | Eddy Rodriguez | 5/31/04 | 2000 | Baltimore |
| 41 | Sendy Rleal | 4/5/06 | 2000-2002 | Baltimore |
| 42 | Eli Whiteside | 7/5/05 | 2001 | Baltimore |
| 43 | Kurt Birkins | 5/4/06 | 2002 | Baltimore |
| 44 | Rommie Lewis | 4/28/10 | 2002 | Toronto |
| 45 | John Maine | 7/23/04 | 2002, 2003 | Baltimore |
| 46 | Val Majewski | 8/20/04 | 2002, 2003 | Baltimore |
| 47 | Scott Rice | 4/1/13 | 2002, 2003 | New York Mets |
| 48 | Daniel Cabrera | 5/13/04 | 2003 | Baltimore |
| 49 | Randy Ruiz | 8/1/08 | 2003 | Minnesota |
| 50 | Jeff Fiorentino | 5/12/05 | 2004 | Baltimore |
| 51 | Hayden Penn | 5/28/05 | 2004 | Baltimore |
| 52 | Chris Ray | 6/14/05 | 2004 | Baltimore |
| 53 | Nick Markakis | 4/3/06 | 2004 | Baltimore |
| 54 | Chris Britton | 4/12/06 | 2004 | Baltimore |
| 55 | Adam Loewen | 5/23/06 | 2004 | Baltimore |
| 56 | Jim Johnson | 7/29/06 | 2004 | Baltimore |
| 57 | Bob McCrory | 4/30/08 | 2004 | Baltimore |
| 58 | Marino Salas | 5/13/08 | 2004 | Pittsburgh |
| 59 | Nate Spears | 7/6/11 | 2004 | Boston |
| 60 | Kevin Hart | 7/4/07 | 2004, 2005 | Chicago Cubs |
| 61 | Radhames Liz | 8/25/07 | 2005 | Baltimore |
| 62 | Jim Hoey | 8/23/06 | 2006 | Baltimore |
| 63 | David Hernandez | 5/28/09 | 2006 | Baltimore |
| 64 | Blake Davis | 6/22/11 | 2006 | Baltimore |
| 65 | Brad Bergesen | 4/21/09 | 2006, 2007 | Baltimore |
| 66 | Brandon Snyder | 7/10/10 | 2006, 2007 | Baltimore |
| 67 | Pedro Beato | 4/1/11 | 2007 | New York Mets |
| 68 | Pedro Florimon | 7/10/11 | 2007, 2008 | Baltimore |
| 69 | Zach Clark | 5/1/13 | 2007, 2008 | Baltimore |
| 70 | Zach Britton | 4/3/11 | 2008 | Baltimore |
| 71 | Ryan Adams | 5/20/11 | 2008 | Baltimore |
| 72 | Matt Angle | 7/17/11 | 2008 | Baltimore |
| 73 | Joe Mahoney | 7/7/12 | 2008, 2009 | Baltimore |
| 74 | Kyle Hudson | 7/4/11 | 2009 | Baltimore |
| 75 | Xavier Avery | 5/13/12 | 2009 | Baltimore |
| 76 | L.J. Hoes | 9/25/12 | 2009 | Baltimore |
| 77 | Oliver Drake | 5/23/15 | 2009 | Baltimore |
| 78 | Mychal Givens | 6/24/15 | 2010-2013 | Baltimore |
| 79 | Scott Copeland | 5/2/15 | 2010-2011 | Toronto |
| 80 | Ty Kelly | 5/24/16 | 2010-2011 | New York Mets |
| 81 | Manny Machado | 8/9/12 | 2011 | Baltimore |
| 82 | Jonathan Schoop | 9/25/13 | 2011 | Baltimore |
| 83 | Mike Wright | 5/17/15 | 2011 | Baltimore |
| 84 | Jason Gurka | 8/29/15 | 2011 | Colorado |
| 85 | Tim Adleman | 5/1/16 | 2011 | Cincinnati |
| 86 | Ashur Tolliver | 5/27/16 | 2011, 2013 | Baltimore |
| 87 | Parker Bridwell | 8/21/16 | 2011-2013 | Baltimore |
| 88 | Dylan Bundy | 9/23/12 | 2012 | Baltimore |
| 89 | Tyler Wilson | 5/20/15 | 2012 | Baltimore |
| 90 | Eduardo Rodriguez | 5/28/15 | 2012 | Boston |
| 91 | Zach Davies | 9/2/15 | 2012 | Milwaukee |
| 92 | Christian Walker | 9/17/14 | 2013 | Baltimore |
| 93 | Steven Brault | 7/5/16 | 2014 | Pittsburgh |
| 94 | Donnie Hart | 7/17/16 | 2014, 2015 | Baltimore |
| 95 | Trey Mancini | 9/20/16 | 2014 | Baltimore |
| 96 | Stefan Crichton | 4/14/17 | 2015 | Baltimore |
| 97 | Mike Ohlman | 5/8/17 | 2010-2012 | Toronto |
| 98 | Josh Hader | 6/9/17 | 2013 | Milwaukee |
| 99 | Jimmy Yacabonis | 6/11/17 | 2014 | Baltimore |
| 100 | Nicky Delmonico | 8/1/17 | 2012 | Chicago White Sox |
| 101 | Chance Sisco | 9/1/17 | 2014 | Baltimore |
| 102 | Tanner Scott | 9/20/17 | 2015 | Baltimore |
| 103 | David Hess | 5/12/18 | 2014 | Baltimore |
| 104 | Austin Wynns | 6/5/18 | 2014 | Baltimore |
| 105 | Steve Wilkerson | 6/20/18 | 2015 | Baltimore |
| 106 | Ryan Meisinger | 6/29/18 | 2016 | Baltimore |
| 107 | Cedric Mullins | 8/10/18 | 2016 | Baltimore |
| 108 | DJ Stewart | 9/12/18 | 2016 | Baltimore |
| 109 | John Means | 9/26/18 | 2015 | Baltimore |
| 110 | Branden Kline | 4/20/19 | 2013 | Baltimore |
| 111 | Mike Yastrzemski | 5/25/19 | 2014 | San Francisco |
| 112 | Hunter Harvey | 8/17/19 | 2014 & 2017 | Baltimore |
| 113 | YermÃn Mercedes | 8/2/20 | 2015 & 2016 | Chicago White Sox |
| 114 | Ryan Mountcastle | 8/21/20 | 2016 | Baltimore |
| 115 | Jonah Heim | 8/25/20 | 2015 | Oakland |
| 116 | Garrett Cleavinger | 9/17/20 | 2016 | Philadelphia |
| 117 | Ryan McKenna | 4/5/21 | 2017 | Baltimore |
| 118 | Zac Lowther | 4/25/21 | 2018 | Baltimore |
| 119 | Jay Flaa | 4/27/21 | 2016 | Baltimore |
| 120 | Alex Wells | 6/26/21 | 2017 | Baltimore |
| 121 | Mike Baumann | 9/7/21 | 2018 & 2021 | Baltimore |