Harrisburg Senators Roster & Staff
WSH Transactions
| Date | Transaction |
| 04/08/22 | Harrisburg Senators transferred C Allan Berrios to the Development List. |
| 04/08/22 | RHP Dakody Clemmer assigned to Harrisburg Senators. |
| 04/08/22 | RHP Andrew Lee assigned to Harrisburg Senators. |
| 04/08/22 | RHP Cole Henry assigned to Harrisburg Senators. |
| 04/08/22 | OF Justin Connell assigned to Harrisburg Senators. |
| 04/08/22 | Harrisburg Senators transferred RHP Francys Peguero to the Development List. |
| 04/08/22 | LHP Brian Gonzalez assigned to Harrisburg Senators. |
| 04/08/22 | SS Gilbert Lara assigned to Harrisburg Senators. |
| 04/08/22 | SS Jack Dunn assigned to Harrisburg Senators. |
| 04/08/22 | RHP Matt Brill assigned to Harrisburg Senators. |
| 04/08/22 | Harrisburg Senators placed LHP Luis Avilan on the 7-day injured list. |
| 04/08/22 | CF Rudy Martin assigned to Harrisburg Senators. |
| 04/08/22 | RHP Ramon Santos assigned to Harrisburg Senators. |
| 04/08/22 | Harrisburg Senators activated RHP Steven Fuentes. |
| 04/08/22 | LF Mitch Longo assigned to Harrisburg Senators. |
| 04/08/22 | C Taylor Gushue assigned to Harrisburg Senators. |
| 04/08/22 | Harrisburg Senators placed CF Rudy Martin on the 7-day injured list. |
| 04/08/22 | RHP Alberto Guerrero assigned to Harrisburg Senators from Rochester Red Wings. |
| 04/08/22 | SS Cole Daily assigned to Wilmington Blue Rocks from Harrisburg Senators. |
| 04/08/22 | OF Gage Canning assigned to Wilmington Blue Rocks from Harrisburg Senators. |
| 04/08/22 | Rochester Red Wings placed RHP Logan Verrett on the 7-day injured list. |
| 04/08/22 | RHP Alberto Guerrero assigned to Harrisburg Senators from Rochester Red Wings. |
| 04/08/22 | 2B Darren Baker assigned to Wilmington Blue Rocks. |
| 04/08/22 | C Onix Vega assigned to Wilmington Blue Rocks. |
| 04/08/22 | SS Jordy Barley assigned to Wilmington Blue Rocks. |
| 04/08/22 | Wilmington Blue Rocks placed LHP Alfonso Hernandez on the 7-day injured list. |
| 04/08/22 | LHP Michael Kirian assigned to Wilmington Blue Rocks. |
| 04/08/22 | Wilmington Blue Rocks placed RHP Davis Moore on the 60-day injured list. |
| 04/08/22 | Wilmington Blue Rocks placed RHP Holden Powell on the 7-day injured list. |
| 04/08/22 | Wilmington Blue Rocks placed RHP Tyler Dyson on the 60-day injured list. |
| 04/08/22 | RHP Amos Willingham assigned to Wilmington Blue Rocks. |
| 04/08/22 | Wilmington Blue Rocks placed C Drew Millas on the 7-day injured list. |
| 04/08/22 | Wilmington Blue Rocks placed SS J.T. Arruda on the 7-day injured list. |
| 04/08/22 | LHP Lucas Knowles assigned to Wilmington Blue Rocks. |
| 04/08/22 | RHP Carlos Romero assigned to Wilmington Blue Rocks. |
| 04/08/22 | SS Jose Sanchez assigned to Wilmington Blue Rocks. |
| 04/08/22 | Wilmington Blue Rocks placed CF Ricardo Mendez on the 7-day injured list. |
| 04/08/22 | RHP Matt Merrill assigned to Wilmington Blue Rocks. |
| 04/08/22 | Wilmington Blue Rocks placed RHP Matt Merrill on the 7-day injured list. |
| 04/08/22 | Wilmington Blue Rocks placed C Onix Vega on the 7-day injured list. |
| 04/08/22 | RHP Michael Cuevas assigned to Wilmington Blue Rocks. |
| 04/08/22 | Wilmington Blue Rocks placed RHP Todd Peterson on the 7-day injured list. |
| 04/08/22 | SS Cole Daily assigned to Wilmington Blue Rocks from Harrisburg Senators. |
| 04/08/22 | C Jarrett Gonzales assigned to Wilmington Blue Rocks from FCL Nationals. |
| 04/08/22 | OF Gage Canning assigned to Wilmington Blue Rocks from Harrisburg Senators. |
| 04/07/22 | RHP Orlando Ribalta assigned to Fredericksburg Nationals from FCL Nationals. |
| 04/07/22 | RHP Jack Sinclair assigned to Fredericksburg Nationals from FCL Nationals. |
| 04/07/22 | 2B Yoander Rivero assigned to Fredericksburg Nationals from FCL Nationals. |
| 04/07/22 | SS Brady House assigned to Fredericksburg Nationals from FCL Nationals. |
| 04/07/22 | RHP Bryan Caceres assigned to Fredericksburg Nationals from FCL Nationals. |